Camk4^tm1Gsc
Targeted Allele Detail

Summary

• Symbol: Camk4^tm1Gsc
• Name: calcium/calmodulin-dependent protein kinase IV; targeted mutation 1, Gunther Schutz
• MGI ID: MGI:2181436
• Synonyms: CamkIV^loxP
• Gene: Camk4 Location: Chr18:33067984-33324281 bp, + strand Genetic Position: Chr18, 18.15 cM
• Alliance: Camk4^tm1Gsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A single loxP site was introduced upstream of exon 3 and a loxP site followed by an frt-flanked neomycin and thymidine kinase selection cassette was inserted 3' to exon 3. The selection cassette was removed in ES cells by transient FLPe recombinase expression prior to the production of chimeric mice, leaving loxP sites flanking exon 3 in the final allele. (J:75112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Camk4 Mutation: 39 strains or lines available

References

• Original: J:75112 Casanova E, et al., Conditional mutagenesis of CamKIV. Genesis. 2002 Feb;32(2):161-4
• All: 5 reference(s)