Fgfr1^tm3Cxd
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm3Cxd
• Name: fibroblast growth factor receptor 1; targeted mutation 3, Chu-Xia Deng
• MGI ID: MGI:2181471
• Synonyms: Fgfr1^neo-Co
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm3Cxd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75137
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A single loxP site was introduced 5' to exon 8 and a loxP-flanked neomycin resistance cassette was inserted 3' to exon 14. This mutation interferes with normal spicing of the encoded transcript. (J:75137)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 223 strains or lines available

References

• Original: J:75137 Xu X, et al., Generation of Fgfr1 conditional knockout mice. Genesis. 2002 Feb;32(2):85-6
• All: 1 reference(s)