Fgfr1^tm3.2Cxd
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm3.2Cxd
• Name: fibroblast growth factor receptor 1; targeted mutation 3.2, Chu-Xia Deng
• MGI ID: MGI:2181474
• Synonyms: Fgfr1^Co, Fgfr1^f
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm3.2Cxd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75137
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: This heritable allele is a derivative of Fgfr1^tm3Cxd in which the loxP flanked neomycin resistance cassette was deleted by Cre mediated recombination, leaving loxP sites flanking exons 8-14 in the final allele. (J:75137)

Expression

In Mice Carrying this Mutation:	3 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 223 strains or lines available

References

• Original: J:75137 Xu X, et al., Generation of Fgfr1 conditional knockout mice. Genesis. 2002 Feb;32(2):85-6
• All: 39 reference(s)