Ptger2tm1Rsz
Targeted Allele Detail
|
|
| Symbol: |
Ptger2tm1Rsz |
| Name: |
prostaglandin E receptor 2 (subtype EP2); targeted mutation 1, Lawrence G Raisz |
| MGI ID: |
MGI:2181616 |
| Synonyms: |
EP2 - |
| Gene: |
Ptger2 Location: Chr14:45225652-45241277 bp, + strand Genetic Position: Chr14, 22.68 cM
|
| Alliance: |
Ptger2tm1Rsz page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:77408
|
| Parent Cell Line: |
TL1/TL-1 (ES Cell)
|
| Strain of Origin: |
129S6/SvEvTac
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutations: |
|
Insertion, Intragenic deletion
|
| |
|
Mutation details: A portion of the amino-terminal coding sequence was replaced with a PGK-neo cassette. RT-PCR analysis showed a lack of transcript in spleen cells obtained from homozygous mutant mice.
(J:77408)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Ptger2 Mutation: |
31 strains or lines available
|
|
| Original: |
J:77408 Li X, et al., Knockout of the murine prostaglandin EP2 receptor impairs osteoclastogenesis in vitro. Endocrinology. 2000 Jun;141(6):2054-61 |
| All: |
1 reference(s) |
|
Analysis Tools
