Phex^Hyp-2J
Spontaneous Allele Detail

Summary

• Symbol: Phex^Hyp-2J
• Name: phosphate regulating endopeptidase homolog, X-linked; hypophosphatemia 2 Jackson
• MGI ID: MGI:2181653
• Gene: Phex Location: ChrX:155945071-156198282 bp, - strand Genetic Position: ChrX, 72.38 cM
• Alliance: Phex^Hyp-2J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A deletion of at least 7.3 kb containing exon 15 of the Phex gene was identified and confirmed by RT-PCR, genomic PCR and Southern blot analysis (J:88352)

Disease models

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Phex Mutation: 22 strains or lines available

References

• Original: J:88352 Lorenz-Depiereux B, et al., New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice. Mamm Genome. 2004 Mar;15(3):151-61
• All: 5 reference(s)