Cd9tm1Mek
Targeted Allele Detail
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Symbol: |
Cd9tm1Mek |
Name: |
CD9 antigen; targeted mutation 1, Eisuke Mekada |
MGI ID: |
MGI:2181695 |
Synonyms: |
CD9- |
Gene: |
Cd9 Location: Chr6:125437229-125471723 bp, - strand Genetic Position: Chr6, 59.32 cM
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Alliance: |
Cd9tm1Mek page
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Germline Transmission: |
Earliest citation of germline transmission:
J:59402
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Sequence, encompassing a portion of exon 3 and all of exon 4 and encoding the second and third transmembrane domains, was replaced with a neomycin selection cassette. Flow cytometric analysis showed an absence of encoded protein on the surface of bone marrow cells obtained from homozygous mutant mice. An absence of protein expression on homozygous mutant oocyte plasma membranes was determined via immunofluorescent staining.
(J:59402)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cd9 Mutation: |
104 strains or lines available
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Original: |
J:59402 Miyado K, et al., Requirement of CD9 on the egg plasma membrane for fertilization. Science. 2000 Jan 14;287(5451):321-4 |
All: |
26 reference(s) |
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