Foxe1^tm1Rdl
Targeted Allele Detail

Summary

• Symbol: Foxe1^tm1Rdl
• Name: forkhead box E1; targeted mutation 1, Roberto Di Lauro
• MGI ID: MGI:2181780
• Synonyms: Titf2-
• Gene: Foxe1 Location: Chr4:46343644-46345774 bp, + strand Genetic Position: Chr4, 24.68 cM
• Alliance: Foxe1^tm1Rdl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48970
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin selection cassette was inserted 180 base pairs upstream of the translational start codon. (J:48970)

Disease models

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxe1 Mutation: 11 strains or lines available

References

• Original: J:48970 De Felice M, et al., A mouse model for hereditary thyroid dysgenesis and cleft palate. Nat Genet. 1998 Aug;19(4):395-8
• All: 5 reference(s)