Zbtb16^tm1Ppp
Targeted Allele Detail

Summary

• Symbol: Zbtb16^tm1Ppp
• Name: zinc finger and BTB domain containing 16; targeted mutation 1, Pier Paolo Pandolfi
• MGI ID: MGI:2182708
• Synonyms: PLZF^-
• Gene: Zbtb16 Location: Chr9:48565597-48747522 bp, - strand Genetic Position: Chr9, 26.47 cM
• Alliance: Zbtb16^tm1Ppp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:62547
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3.5 kb genomic fragment containing the 5' coding region was replaced with a neomycin resistance cassette. Western blot analysis on extracts from homozygous mice confirmed that no detectable protein was made from this allele. (J:62547)

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	21 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Zbtb16^tm1Ppp

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb16 Mutation: 30 strains or lines available

References

• Original: J:62547 Barna M, et al., Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72
• All: 31 reference(s)