Gab2^tm1Hhg
Targeted Allele Detail

Summary

• Symbol: Gab2^tm1Hhg
• Name: growth factor receptor bound protein 2-associated protein 2; targeted mutation 1, Haihua Gu
• MGI ID: MGI:2182762
• Synonyms: Gab2^-
• Gene: Gab2 Location: Chr7:96730958-96958158 bp, + strand Genetic Position: Chr7, 53.39 cM, cytoband E2
• Alliance: Gab2^tm1Hhg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:70424
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with an SA-lacZ-PGK-neo cassette via homologous recombination. Protein product was undetectable in various tissues from homozygous mutant animals as determined by Western blot analysis. (J:70424)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gab2 Mutation: 37 strains or lines available

References

• Original: J:70424 Gu H, et al., Essential role for Gab2 in the allergic response. Nature. 2001 Jul 12;412(6843):186-90
• All: 6 reference(s)