Eomes^tm1Apr
Targeted Allele Detail

Summary

• Symbol: Eomes^tm1Apr
• Name: eomesodermin; targeted mutation 1, Andreas P Russ
• MGI ID: MGI:2182814
• Synonyms: Eo^LacZ, Eomes-
• Gene: Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
• Alliance: Eomes^tm1Apr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:60897
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Portions of exon 2 and intron 2 were replaced with a cassette containing IRES-lacZ and neo. The expression pattern of the lacZ reporter transgene lagged that of the endogenous gene but was otherwise similar. (J:60897)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eomes Mutation: 44 strains or lines available

References

• Original: J:60897 Russ AP, et al., Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature. 2000 Mar 2;404(6773):95-9
• All: 5 reference(s)