Fabp5^tm1Kdo
Targeted Allele Detail

Summary

• Symbol: Fabp5^tm1Kdo
• Name: fatty acid binding protein 5, epidermal; targeted mutation 1, Hisatake Kondo
• MGI ID: MGI:2182961
• Gene: Fabp5 Location: Chr3:10077645-10081670 bp, + strand Genetic Position: Chr3, 2.47 cM, cytoband A1-A3
• Alliance: Fabp5^tm1Kdo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75715
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 4 were replaced by a cassette containing a nls-lacZ gene followed by a floxed neomycin gene. Neither transcript nor protein was detected in skin of homozygous mutant mice by Northern and Western blot analyses. (J:75715)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fabp5 Mutation: 16 strains or lines available

References

• Original: J:75715 Owada Y, et al., Altered water barrier function in epidermal-type fatty acid binding protein-deficient mice. J Invest Dermatol. 2002 Mar;118(3):430-5
• All: 11 reference(s)