Mapk8ip1^tm1Wae
Targeted Allele Detail

Summary

• Symbol: Mapk8ip1^tm1Wae
• Name: mitogen-activated protein kinase 8 interacting protein 1; targeted mutation 1, Gerard Waeber
• MGI ID: MGI:2182967
• Synonyms: IB1/JIP-1^-
• Gene: Mapk8ip1 Location: Chr2:92214021-92231608 bp, - strand Genetic Position: Chr2, 50.99 cM, cytoband E1
• Alliance: Mapk8ip1^tm1Wae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:70600
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3-8 were replaced with a PGK-neo cassette via homologous recombination. Genotype analysis identified 1 homozygous mutant at 3.5 days post coitum out of 148 embryos analyzed. (J:70600)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk8ip1 Mutation: 34 strains or lines available

References

• Original: J:70600 Thompson NA, et al., Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice. J Biol Chem. 2001 Jul 27;276(30):27745-8
• All: 2 reference(s)