Rev3l^tm1Ndew
Targeted Allele Detail

Summary

• Symbol: Rev3l^tm1Ndew
• Name: REV3 like, DNA directed polymerase zeta catalytic subunit; targeted mutation 1, Niels De Wind
• MGI ID: MGI:2183197
• Synonyms: Rev3^-
• Gene: Rev3l Location: Chr10:39608114-39751207 bp, + strand Genetic Position: Chr10, 21.04 cM
• Alliance: Rev3l^tm1Ndew page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75450
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 10 kb region of the gene encoding DNA polymerase domains I, II, III, and IV, was replaced with a PGK-hygro cassette by homologous recombination. (J:75450)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rev3l Mutation: 120 strains or lines available

References

• Original: J:75450 Van Sloun PP, et al., Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol Cell Biol. 2002 Apr;22(7):2159-69
• All: 2 reference(s)