Pspn^tm1Bjh
Targeted Allele Detail

Summary

• Symbol: Pspn^tm1Bjh
• Name: persephin; targeted mutation 1, Brian J Hoffer
• MGI ID: MGI:2183393
• Synonyms: Pspn -
• Gene: Pspn Location: Chr17:57306457-57307018 bp, - strand Genetic Position: Chr17, 29.62 cM, cytoband D
• Alliance: Pspn^tm1Bjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77733
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 2 with a PGK-neo cassette via homologous recombination. Homozygous mutant animals were identified by PCR genotype analysis. (J:77733)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pspn Mutation: 5 strains or lines available

References

• Original: J:77733 Tomac AC, et al., Effects of cerebral ischemia in mice deficient in Persephin. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9521-6
• All: 2 reference(s)