Pth1r^tm2Hmk
Targeted Allele Detail

Summary

• Symbol: Pth1r^tm2Hmk
• Name: parathyroid hormone 1 receptor; targeted mutation 2, Henry M Kronenberg
• MGI ID: MGI:2183512
• Synonyms: Ppr^fl
• Gene: Pth1r Location: Chr9:110551153-110576213 bp, - strand Genetic Position: Chr9, 60.56 cM, cytoband F
• Alliance: Pth1r^tm2Hmk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77683
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 1 was flanked by an upstream neo cassette containing a 3' loxP site and another loxP site in intron 1. (J:77683)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pth1r Mutation: 29 strains or lines available

References

• Original: J:77683 Kobayashi T, et al., PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development. 2002 Jun;129(12):2977-86
• All: 30 reference(s)