Tspan32^{Gt(pMS-1)1Jmt}
Gene trapped Allele Detail

Summary

• Symbol: Tspan32^{Gt(pMS-1)1Jmt}
• Name: tetraspanin 32; gene trap 1, Jacqueline M Tarrant
• MGI ID: MGI:2183564
• Synonyms: Phemx^{Gt(IRES-Beta-geo)1Jmt}, Tssc6^-, Tssc6^gt/gt
• Gene: Tspan32 Location: Chr7:142558644-142573223 bp, + strand Genetic Position: Chr7, 88.09 cM
• Alliance: Tspan32^{Gt(pMS-1)1Jmt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78033
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector was inserted into intron 3. Neither full-length nor truncated transcript was detected via Northern blot or RT-PCR analyses using probes for the 5' and 3' termini. (J:78033)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspan32 Mutation: 30 strains or lines available

References

• Original: J:78033 Tarrant JM, et al., The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses. Mol Cell Biol. 2002 Jul;22(14):5006-18
• All: 4 reference(s)