Tg(APP)6209Kha
Transgene Detail

Summary

• Symbol: Tg(APP)6209Kha
• Name: transgene insertion 6209, Karen Hsiao Ashe
• MGI ID: MGI:2183649
• Synonyms: Tg6209, Tg(APP)6209Kahs, Tg(HuAPP695.WTmyc)6209
• Transgene: Tg(APP)6209Kha Location: unknown
• Alliance: Tg(APP)6209Kha page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APP)6209Kha expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APP (351)

  App	(MGI:88059)

• Mutation details: Overexpression of the human APP gene encoding APP695.WTmyc (wild-type with a 3'-myc tag). The construct contained the APP gene fused to the hamster prion protein promoter. APP expression was measured in brains of transgenic mice by quantitation of immunoblots. (J:29880)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:29880 Hsiao KK, et al., Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron. 1995 Nov;15(5):1203-18
• All: 8 reference(s)