Crabp1^tm1Ipc
Targeted Allele Detail

Summary

• Symbol: Crabp1^tm1Ipc
• Name: cellular retinoic acid binding protein I; targeted mutation 1, Pierre Chambon
• MGI ID: MGI:2183739
• Synonyms: CRABPI H&R
• Gene: Crabp1 Location: Chr9:54672032-54680394 bp, + strand Genetic Position: Chr9, 29.76 cM
• Alliance: Crabp1^tm1Ipc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:20442
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A hit and run type vector was used to create a 5 bp insertion in exon 1 at the fifth codon. Western blot analysis on extracts derived from E13.5 homozygous mice confirmed that no detectable protein was produced from this allele. (J:20442)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crabp1 Mutation: 18 strains or lines available

References

• Original: J:20442 Gorry P, et al., The cellular retinoic acid binding protein I is dispensable. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9032-6
• All: 8 reference(s)