Summary |
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Transgene origin |
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Transgene description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Disease models |
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Find Mice (IMSR) |
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Notes |
Founder 247 is representative of 2 founders (247 and 249) carrying approximately 30 copies of the transgene and exhibiting similar phenotypes. Transgenic animals display slight shivering at 2 weeks of age most apparent in the head. At 4 weeks the animals exhibit unsteady gait and progress to muscle atrophy at 2-3 months leading eventually to hind limb paralysis.
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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