Summary |
|
|||||||||||||
Transgene origin |
|
|||||||||||||
Transgene description |
|
|||||||||||||
Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
|
|||||||||||||
Disease models |
|
|||||||||||||
Find Mice (IMSR) |
|
|||||||||||||
Notes |
Founder 247 is representative of 2 founders (247 and 249) carrying approximately 30 copies of the transgene and exhibiting similar phenotypes. Transgenic animals display slight shivering at 2 weeks of age most apparent in the head. At 4 weeks the animals exhibit unsteady gait and progress to muscle atrophy at 2-3 months leading eventually to hind limb paralysis.
|
|||||||||||||
References |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/29/2024 MGI 6.24 |
|
|