G6pdx^a-m2Neu
Radiation induced Allele Detail

Summary

• Symbol: G6pdx^a-m2Neu
• Name: glucose-6-phosphate dehydrogenase X-linked; mutation 2, Neuherberg
• MGI ID: MGI:2183760
• Gene: G6pdx Location: ChrX:73453089-73472486 bp, - strand Genetic Position: ChrX, 38.0 cM, cytoband A2-A3
• Alliance: G6pdx^a-m2Neu page

Mutation origin

• Strain of Origin: (102/El x C3H/El)F1

Mutation description

• Allele Type: Radiation induced (Hypomorph)
• Mutation: Intragenic deletion
• Mutation details: This is a hypomorphic allele; in hemizygous males, heterozygous females, and homozygous females, the activity level in blood is ~33%, ~65%, and ~29% of normal, respectively. The mutation has been identified as the deletion of exon 6 (159 base pairs). (J:82809, J:89396)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any G6pdx Mutation: 8 strains or lines available

References

• Original: J:89396 Baader SL, et al., Purkinje cell lineage and the topographic organization of the cerebellar cortex: a view from X inactivation mosaics. Dev Biol. 1996 Mar 15;174(2):393-406
• All: 4 reference(s)