Ucntm1Klee
Targeted Allele Detail
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| Symbol: |
Ucntm1Klee |
| Name: |
urocortin; targeted mutation 1, Kuo-Fen Lee |
| MGI ID: |
MGI:2384136 |
| Synonyms: |
Ucn- |
| Gene: |
Ucn Location: Chr5:31295407-31296173 bp, - strand Genetic Position: Chr5, 17.11 cM
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| Alliance: |
Ucntm1Klee page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:78199
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The region encoding the mature peptide was deleted by the insertion of a neomycin selection cassette. The absence of transcript in homozygous mutant mice was demonstrated by RNAse protection and in situ hybridization. Western blot analysis of brain tissue confirmed the lack of protein.
(J:78199)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ucn Mutation: |
4 strains or lines available
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| Original: |
J:78199 Vetter DE, et al., Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior. Nat Genet. 2002 Aug;31(4):363-9 |
| All: |
6 reference(s) |
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Analysis Tools
