Trpv3^Nh
Spontaneous Allele Detail

Summary

• Symbol: Trpv3^Nh
• Name: transient receptor potential cation channel, subfamily V, member 3; non-hair
• MGI ID: MGI:2384170
• Gene: Trpv3 Location: Chr11:73158315-73191194 bp, + strand Genetic Position: Chr11, 45.25 cM
• Alliance: Trpv3^Nh page

Mutation origin

• Strain of Origin: DS

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A phenotypic mutant associated with severe dermititis identified in a colony of DS mice. A c.1717G>A point mutation in this allele results in glycine 573 being replaced with serine (p.G573S). (J:116026)
• Inheritance: Dominant

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Trpv3 Mutation: 55 strains or lines available

References

• Original: J:42153 Haraguchi M, et al., Naturally occurring dermatitis associated with Staphylococcus aureus in DS-Nh mice. Exp Anim. 1997 Jul;46(3):225-9
• All: 8 reference(s)