Cd79a^{tm1(BAP31N-EGFP)Pld}
Targeted Allele Detail

Summary

• Symbol: Cd79a^{tm1(BAP31N-EGFP)Pld}
• Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 1, Roberta Pelanda
• MGI ID: MGI:2384630
• Synonyms: mb-1/mEGFP^inv
• Gene: Cd79a Location: Chr7:24596922-24601283 bp, + strand Genetic Position: Chr7, 13.49 cM
• Alliance: Cd79a^{tm1(BAP31N-EGFP)Pld} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75114
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 5 were replaced by a fragment flanked by inverted loxP sites containing the cDNA for exons 2 through 5 followed downstream by a polyA signal and, in opposite orientation, sequence encoding a membrane-associated enhanced green fluorescent protein (GFP). The absence of GFP and the expression of endogenous protein was confirmed by flow cytometric analysis of bone marrow, spleen, and lymph node cells. (J:75114)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79a Mutation: 24 strains or lines available

References

• Original: J:75114 Pelanda R, et al., Cre recombinase-controlled expression of the mb-1 allele. Genesis. 2002 Feb;32(2):154-7
• All: 4 reference(s)