Mdm2^tm1Snj
Targeted Allele Detail

Summary

• Symbol: Mdm2^tm1Snj
• Name: transformed mouse 3T3 cell double minute 2; targeted mutation 1, Steven N Jones
• MGI ID: MGI:2385452
• Synonyms: Mdm2^SJcnd1
• Gene: Mdm2 Location: Chr10:117524780-117546663 bp, - strand Genetic Position: Chr10, 66.32 cM, cytoband C1-C3
• Alliance: Mdm2^tm1Snj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75119
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed region containing exons 11 and 12 and a neo cassette 560 base pairs downstream of the polyA signal was inserted at the endogenous locus via homologous recombination. (J:75119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdm2 Mutation: 54 strains or lines available

References

• Original: J:75119 Steinman HA, et al., Generation of an Mdm2 conditional allele in mice. Genesis. 2002 Feb;32(2):142-4
• All: 3 reference(s)