Tg(TLK2mHEL)2Ccg
Transgene Detail
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| Symbol: |
Tg(TLK2mHEL)2Ccg |
| Name: |
transgene insertion 2, Christopher C Goodnow |
| MGI ID: |
MGI:2385453 |
| Synonyms: |
thyroHEL, TLK-2 |
| Transgene: |
Tg(TLK2mHEL)2Ccg Location: unknown
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| Alliance: |
Tg(TLK2mHEL)2Ccg page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A genomic fragment containing the coding exons of the chicken lysozyme gene (also known as hen egg lysozyme, HEL) was linked to a 3.3kb fragment of the rat thyroglobulin promoter and to the mouse H2-Kb transmembrane sequence (which included the extracellular spacer sequence, transmembrane segment, and cytoplasmic tail). Thyroids from mice carrying the transgene showed expression of chicken lysozyme by Western blot; spleen, islets, and thymus did not.
(J:78309)
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| Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:78309 Akkaraju S, et al., A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. Immunity. 1997 Aug;7(2):255-71 |
| All: |
2 reference(s) |
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Analysis Tools
