Hnf4a^tm1Sad
Targeted Allele Detail

Summary

• Symbol: Hnf4a^tm1Sad
• Name: hepatic nuclear factor 4, alpha; targeted mutation 1, Stephen A Duncan
• MGI ID: MGI:2385463
• Synonyms: hnf4alpha^loxP
• Gene: Hnf4a Location: Chr2:163348731-163414827 bp, + strand Genetic Position: Chr2, 84.32 cM
• Alliance: Hnf4a^tm1Sad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75121
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Single loxP sites in introns 1 and 2 flanked exon 2. (J:75121)

Disease models

Expression

In Mice Carrying this Mutation:	226 assay results 5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hnf4a Mutation: 28 strains or lines available

References

• Original: J:75121 Parviz F, et al., Generation of a conditionally null allele of hnf4alpha. Genesis. 2002 Feb;32(2):130-3
• All: 12 reference(s)