Lhx4^tm1Ssp
Targeted Allele Detail

Summary

• Symbol: Lhx4^tm1Ssp
• Name: LIM homeobox protein 4; targeted mutation 1, S Steven Potter
• MGI ID: MGI:2385815
• Gene: Lhx4 Location: Chr1:155573777-155627430 bp, - strand Genetic Position: Chr1, 67.47 cM
• Alliance: Lhx4^tm1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:19373
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• 0.7 kb of sequence encoding the homeobox domain was replaced with a neomycin selection cassette. (J:19373)

Expression

In Mice Carrying this Mutation:	27 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lhx4 Mutation: 25 strains or lines available

References

• Original: J:19373 Li H, et al., Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival. EMBO J. 1994 Jun 15;13(12):2876-85
• All: 8 reference(s)