Mafk^tm1Sho
Targeted Allele Detail

Summary

• Symbol: Mafk^tm1Sho
• Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); targeted mutation 1, Stuart Orkin
• MGI ID: MGI:2385844
• Synonyms: p18 NF-E2 -
• Gene: Mafk Location: Chr5:139777291-139788409 bp, + strand Genetic Position: Chr5, 78.81 cM
• Alliance: Mafk^tm1Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35116
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The third exon, encoding most of the protein including the basic zipper domain, was replaced by a neomycin selection cassette. (J:35116)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mafk Mutation: 14 strains or lines available

References

• Original: J:35116 Kotkow KJ, et al., Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3514-8
• All: 1 reference(s)