Nbl1^tm2Rmh
Targeted Allele Detail

Summary

• Symbol: Nbl1^tm2Rmh
• Name: NBL1, DAN family BMP antagonist; targeted mutation 2, Richard M Harland
• MGI ID: MGI:2385845
• Synonyms: Dan^PLAP
• Gene: Nbl1 Location: Chr4:138809595-138820304 bp, - strand Genetic Position: Chr4, 70.57 cM, cytoband D3
• Alliance: Nbl1^tm2Rmh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67351
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Portions of exons 1 and 2 were replaced with a cassette containing a PGK-neo gene and an IRES adjoined to the placental alkaline phosphatase gene. (J:67351)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nbl1 Mutation: 16 strains or lines available

References

• Original: J:67351 Dionne MS, et al., Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists. Mol Cell Biol. 2001 Jan;21(2):636-43
• All: 1 reference(s)