Dmrt1^tm1Zark
Targeted Allele Detail

Summary

• Symbol: Dmrt1^tm1Zark
• Name: doublesex and mab-3 related transcription factor 1; targeted mutation 1, David Zarkower
• MGI ID: MGI:2385911
• Synonyms: Dmrt1^flox, Dmrt1^neo
• Gene: Dmrt1 Location: Chr19:25483070-25581692 bp, + strand Genetic Position: Chr19, 20.45 cM, cytoband C2-C3
• Alliance: Dmrt1^tm1Zark page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The entire exon 1 was floxed by insertion of a loxP site upstream of the promoter and insertion of a PGK-neo-loxP cassette at intron 1 via homologous recombination. (J:65541)

Expression

In Mice Carrying this Mutation:

6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmrt1 Mutation: 49 strains or lines available

References

• Original: J:65541 Raymond CS, et al., Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 2000 Oct 15;14(20):2587-95
• All: 11 reference(s)