Tg(Tie1-cre)9Ref
Transgene Detail

Summary

• Symbol: Tg(Tie1-cre)9Ref
• Name: transgene insertion 9, Reinhard Fassler
• MGI ID: MGI:2385916
• Synonyms: Tie-1-Cre, Tie1-Cre
• Transgene: Tg(Tie1-cre)9Ref Location: unknown
• Alliance: Tg(Tie1-cre)9Ref page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:67916
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tie1-cre)9Ref expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tie1 (MGI:99906)

• Mutation details: The transgene is composed of a 1.15 kb fragment of mouse Tie1 promoter fused to the cre recombinase gene and a nuclear localization signal, and a separate floxed PGK-neo cassette. The mouse Tie1 promoter directs expression of the cre transgene in endothelial cells. (J:67916)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tie1 (mouse) Summary of all recombinase alleles driven by Tie1. Comparative matrix view of recombinase activities Alliance mouse Tie1 gene page

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:67916 Gustafsson E, et al., Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice. J Cell Sci. 2001 Feb;114(Pt 4):671-6
• All: 50 reference(s)