Rxra^tm1.1Krc
Targeted Allele Detail

Summary

• Symbol: Rxra^tm1.1Krc
• Name: retinoid X receptor alpha; targeted mutation 1.1, Kenneth R Chien
• MGI ID: MGI:2385921
• Gene: Rxra Location: Chr2:27566452-27652969 bp, + strand Genetic Position: Chr2, 19.38 cM
• Alliance: Rxra^tm1.1Krc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48085
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 4 was removed by loxP-mediated recombination by crossing animals carrying Rxra^tm1Krc to the Tg(Prm-cre)58Og line which expresses cre recombinase in the spermatocytes. (J:48085)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rxra Mutation: 30 strains or lines available

References

• Original: J:48085 Chen J, et al., Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development. 1998 May;125(10):1943-9
• All: 1 reference(s)