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Rxratm1.1Krc
Targeted Allele Detail
Summary
Symbol: Rxratm1.1Krc
Name: retinoid X receptor alpha; targeted mutation 1.1, Kenneth R Chien
MGI ID: MGI:2385921
Gene: Rxra  Location: Chr2:27566452-27652969 bp, + strand  Genetic Position: Chr2, 19.38 cM
Alliance: Rxratm1.1Krc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48085
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 4 was removed by loxP-mediated recombination by crossing animals carrying Rxratm1Krc to the Tg(Prm-cre)58Og line which expresses cre recombinase in the spermatocytes. (J:48085)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rxra Mutation:  30 strains or lines available
References
Original:  J:48085 Chen J, et al., Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development. 1998 May;125(10):1943-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory