Eportm1.2Jtp
Targeted Allele Detail
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Symbol: |
Eportm1.2Jtp |
Name: |
erythropoietin receptor; targeted mutation 1.2, Josef T Prchal |
MGI ID: |
MGI:2386092 |
Synonyms: |
EporH, wth, wthEPOR, wthEPORdeltaneo, wthEPORdeltaneo/cre |
Gene: |
Epor Location: Chr9:21870193-21874802 bp, - strand Genetic Position: Chr9, 7.93 cM
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Alliance: |
Eportm1.2Jtp page
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Germline Transmission: |
Earliest citation of germline transmission:
J:67205
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Parent Cell Line: |
HM-1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd-Hprt1b-m3
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Allele Type: |
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Targeted (Humanized sequence, Inserted expressed sequence) |
Mutations: |
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Insertion, Intragenic deletion
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Eportm1.2Jtp expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
EPOR (2057) |
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Mutation details: This knock-in allele contains human sequence of the EPOR gene from the translational start site to the stop codon. It is a derivative of Eportm1.1Jtp in which cre-mediated recombination in vivo removed the PGK-neo cassette in the germline. RT-PCR analysis of bone marrow detected human transcript in homozygous mutant mice.
(J:67205)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Epor Mutation: |
26 strains or lines available
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Original: |
J:67205 Divoky V, et al., Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):986-91 |
All: |
6 reference(s) |
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