Rarbtm2Ipc
Targeted Allele Detail
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Symbol: |
Rarbtm2Ipc |
Name: |
retinoic acid receptor, beta; targeted mutation 2, Pierre Chambon |
MGI ID: |
MGI:2386108 |
Synonyms: |
RARbetaL2 |
Gene: |
Rarb Location: Chr14:5650540-6038924 bp, + strand Genetic Position: Chr14, 7.08 cM, cytoband A1-A3
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Alliance: |
Rarbtm2Ipc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:75134
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exons 9 and 10, which encode amino acids 263 through 384 encompassing most of the ligand binding domain, were left flanked by loxP sites after the in vitro cre-mediated excision of a selection cassette. Both isoforms produced by the endogenous gene were detected in homozygous mutant mice, verifying that the presence of the loxP sites did not affect gene function.
(J:75134)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rarb Mutation: |
40 strains or lines available
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Original: |
J:75134 Chapellier B, et al., A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) gene. Genesis. 2002 Feb;32(2):91-4 |
All: |
13 reference(s) |
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