Smad1^tm1Abr
Targeted Allele Detail

Summary

• Symbol: Smad1^tm1Abr
• Name: SMAD family member 1; targeted mutation 1, Anita B Roberts
• MGI ID: MGI:2386127
• Synonyms: Smad1^flox, Smad1^fx, Smad1^fx(exon2), Smad^fl
• Gene: Smad1 Location: Chr8:80065024-80126057 bp, - strand Genetic Position: Chr8, 37.56 cM
• Alliance: Smad1^tm1Abr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75139
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by an upstream floxed neo cassette and a downstream single loxP site. (J:75139)

Expression

In Mice Carrying this Mutation:	194 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smad1 Mutation: 32 strains or lines available

References

• Original: J:75139 Huang S, et al., Conditional knockout of the Smad1 gene. Genesis. 2002 Feb;32(2):76-9
• All: 23 reference(s)