Piga^tm1.1Tak
Targeted Allele Detail

Summary

• Symbol: Piga^tm1.1Tak
• Name: phosphatidylinositol glycan anchor biosynthesis, class A; targeted mutation 1.1, Junji Takeda
• MGI ID: MGI:2386158
• Gene: Piga Location: ChrX:163202814-163216912 bp, + strand Genetic Position: ChrX, 76.49 cM, cytoband F3-F4
• Alliance: Piga^tm1.1Tak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:53967
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 6 was deleted in the germline by crossing mice carrying Piga^tm1Tak with transgenic mice expressing cre recombinase via the CMV promoter. (J:53967)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Piga Mutation: 3 strains or lines available

References

• Original: J:53967 Nozaki M, et al., Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system. Lab Invest. 1999 Mar;79(3):293-9
• All: 1 reference(s)