Oxttm1Zuk
Targeted Allele Detail
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| Symbol: |
Oxttm1Zuk |
| Name: |
oxytocin; targeted mutation 1, Martin M Matzuk |
| MGI ID: |
MGI:2386203 |
| Synonyms: |
Oxt- |
| Gene: |
Oxt Location: Chr2:130418093-130418974 bp, + strand Genetic Position: Chr2, 63.24 cM
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| Alliance: |
Oxttm1Zuk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:35874
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| Parent Cell Line: |
AB2.1 (ES Cell)
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| Strain of Origin: |
129S7/SvEvBrd-Hprt1b-m2
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 1 was replaced with a PGK-Hprt cassette via homologous recombination. The targeted deletion was confirmed in homozygous mutant animals by Southern blot analysis. In situ hybridization of brain sections verified the absence of gene expression in homozygous mutants.
(J:35874)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Oxt Mutation: |
20 strains or lines available
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| Original: |
J:35874 Nishimori K, et al., Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11699-704 |
| All: |
21 reference(s) |
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Analysis Tools
