Tg(ADRB1)1Srr
Transgene Detail

Summary

• Symbol: Tg(ADRB1)1Srr
• Name: transgene insertion 1, Susan R Ross
• MGI ID: MGI:2386502
• Transgene: Tg(ADRB1)1Srr Location: unknown
• Alliance: Tg(ADRB1)1Srr page

Transgene origin

• Strain of Origin: Swiss Webster

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ADRB1)1Srr expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ADRB1 (153)

  Adrb1

  (MGI:87937)

• Mutation details: This transgene was constructed by fusing a 5.4kb segment of the regulatory region of the mouse lipid-binding protein gene to a 2.4kb fragment of human adrenergic receptor, beta 1 (ADRB1) cDNA. Transgene expression was detected in adipose tissue, but not in any other tissue, by Northern blot. (J:37585)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:37585 Soloveva V, et al., Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity. Mol Endocrinol. 1997 Jan;11(1):27-38
• All: 1 reference(s)