Ppard^tm1Rev
Targeted Allele Detail

Summary

• Symbol: Ppard^tm1Rev
• Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Ronald M Evans
• MGI ID: MGI:2386683
• Synonyms: Ppardelta^ck
• Gene: Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
• Alliance: Ppard^tm1Rev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73557
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 4, which encodes the amino terminal portion of the DNA binding domain was left flanked by single loxP sites after a downstream neo cassette was excised via the expression of cre recombinase in vitro. (J:73557)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppard Mutation: 68 strains or lines available

References

• Original: J:73557 Barak Y, et al., Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8
• All: 38 reference(s)