Hydin^{hy3-Tg(Bdnf)459Ove}
Transgenic Allele Detail

Summary

• Symbol: Hydin^{hy3-Tg(Bdnf)459Ove}
• Name: HYDIN, axonemal central pair apparatus protein; transgene insertion 459, Paul Overbeek
• MGI ID: MGI:2386736
• Synonyms: OVE459
• Gene: Hydin Location: Chr8:110993609-111336885 bp, + strand Genetic Position: Chr8, 57.5 cM
• Alliance: Hydin^{hy3-Tg(Bdnf)459Ove} page

Hydrocephalus in Hydin^{hy3-Tg(Bdnf)459Ove}/Hydin^{hy3-Tg(Bdnf)459Ove} mice

Show the 2 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic
• Mutation: Insertion
• Mutation details: A transgene expressing Bdnf inserted randomly into the hy3 gene. Matings between mice carrying this allele and hy3 mice demonstrated that these two mutations fail to complement each other, and suggests that these two mutations are allelic and very likely result from disrupted function of the same gene or set of genes. (J:83437)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hydin Mutation: 228 strains or lines available

References

• Original: J:80595 Robinson ML, et al., Genetic mapping of an insertional hydrocephalus-inducing mutation allelic to hy3. Mamm Genome. 2002 Nov;13(11):625-32
• All: 3 reference(s)