Fth1^tm1Cbea
Targeted Allele Detail

Summary

• Symbol: Fth1^tm1Cbea
• Name: ferritin heavy polypeptide 1; targeted mutation 1, Carole Beaumont
• MGI ID: MGI:2386942
• Synonyms: Fth^-
• Gene: Fth1 Location: Chr19:9957962-9962462 bp, + strand Genetic Position: Chr19, 6.23 cM, cytoband A-C
• Alliance: Fth1^tm1Cbea page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:60287
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The last half of exon 2 and part of intron 2 were replaced with a promoterless IRES-betageo cassette via homologous recombination. (J:60287)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fth1 Mutation: 14 strains or lines available

References

• Original: J:60287 Ferreira C, et al., Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem. 2000 Feb 4;275(5):3021-4
• All: 5 reference(s)