Lbx1^tm1Thbr
Targeted Allele Detail

Summary

• Symbol: Lbx1^tm1Thbr
• Name: ladybird homeobox 1; targeted mutation 1, Thomas Braun
• MGI ID: MGI:2386948
• Synonyms: Lbx1(-)
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^tm1Thbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57891
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A cassette containing IRES-lacZ and PGK-neo replaced the homeobox encoding region of exon 2 and 1 kb of fragment of the polyadenylation sequence. (J:57891)

Expression

In Mice Carrying this Mutation:	44 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:57891 Schafer K, et al., Early specification of limb muscle precursor cells by the homeobox gene Lbx1h. Nat Genet. 1999 Oct;23(2):213-6
• All: 3 reference(s)