Incenp^tm1Khac
Targeted Allele Detail

Summary

• Symbol: Incenp^tm1Khac
• Name: inner centromere protein; targeted mutation 1, K H Andy Choo
• MGI ID: MGI:2386970
• Gene: Incenp Location: Chr19:9849659-9876853 bp, - strand Genetic Position: Chr19, 6.1 cM
• Alliance: Incenp^tm1Khac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56343
• Parent Cell Line: GK129 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The gene was disrupted at codon 47 by insertion of a promoter-less IRES-neo cassette into exon 3. (J:56343)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Incenp Mutation: 42 strains or lines available

References

• Original: J:56343 Cutts SM, et al., Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice. Hum Mol Genet. 1999 Jul;8(7):1145-55
• All: 1 reference(s)