Cebpa^tm3Nerl
Targeted Allele Detail

Summary

• Symbol: Cebpa^tm3Nerl
• Name: CCAAT/enhancer binding protein alpha; targeted mutation 3, Claus Nerlov
• MGI ID: MGI:2387094
• Synonyms: Cebpa^WT
• Gene: Cebpa Location: Chr7:34818718-34821353 bp, + strand Genetic Position: Chr7, 21.02 cM
• Alliance: Cebpa^tm3Nerl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72330
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutation: Nucleotide substitutions
• Mutation details: The coding region was replaced with the wild-type coding region followed by a floxed neo cassette in the opposite orientation. (J:72330)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cebpa Mutation: 19 strains or lines available

References

• Original: J:72330 Porse BT, et al., E2f repression by c/ebpalpha is required for adipogenesis and granulopoiesis in vivo. Cell. 2001 Oct 19;107(2):247-58
• All: 3 reference(s)