Klra8^Cmv1-s
Allele Detail

Summary

• Symbol: Klra8^Cmv1-s
• Name: killer cell lectin-like receptor, subfamily A, member 8; cytomegalovirus resistance 1, susceptible
• MGI ID: MGI:2387149
• Synonyms: Cmv1^s
• Gene: Klra8 Location: Chr6:130092189-130106861 bp, - strand Genetic Position: Chr6, 63.44 cM
• Alliance: Klra8^Cmv1-s page

Mutation origin

• Strain of Origin: multiple strains

Mutation description

• Allele Type: Not Applicable
• Mutation: Intragenic deletion
• Mutation details: Most mouse strains other than C57BL/6 and C57BL/10 lack the Klra8 gene, and this correlates with an increased susceptiblity to cytomegalovirus infection. (J:79093)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klra8 Mutation: 18 strains or lines available

Notes

BALB/cJ mice carry this allele.

References

• Original: J:10460 Scalzo AA, et al., Cmv-1, a genetic locus that controls murine cytomegalovirus replication in the spleen. J Exp Med. 1990 May 1;171(5):1469-83
• All: 8 reference(s)