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Tcf3tm3Zhu
Targeted Allele Detail
Summary
Symbol: Tcf3tm3Zhu
Name: transcription factor 3; targeted mutation 3, Yuan Zhuang
MGI ID: MGI:2387352
Synonyms: E2Aheb
Gene: Tcf3  Location: Chr10:80245348-80269481 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance: Tcf3tm3Zhu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47671
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe E12 and E47 specific exons were replaced by a full length human TCF12 cDNA adjoined to an IRES inserted by homologous recombination. Western blot analysis confirmed that the human gene was expressed. (J:47671)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf3 Mutation:  43 strains or lines available
References
Original:  J:47671 Zhuang Y, et al., Functional replacement of the mouse E2A gene with a human HEB cDNA. Mol Cell Biol. 1998 Jun;18(6):3340-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory