Hrh3^tm1Twl
Targeted Allele Detail

Summary

• Symbol: Hrh3^tm1Twl
• Name: histamine receptor H3; targeted mutation 1, Timothy W Lovenberg
• MGI ID: MGI:2387415
• Synonyms: H3R-
• Gene: Hrh3 Location: Chr2:179741258-179746264 bp, - strand Genetic Position: Chr2, 102.62 cM
• Alliance: Hrh3^tm1Twl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79168
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced a 0.7 kb fragment containing exon 1 and part of exon 2. (J:79168)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hrh3 Mutation: 20 strains or lines available

References

• Original: J:79168 Toyota H, et al., Behavioral characterization of mice lacking histamine H(3) receptors. Mol Pharmacol. 2002 Aug;62(2):389-97
• All: 18 reference(s)