Tg(Grik4-cre)G32-4Stl
Transgene Detail

Summary

• Symbol: Tg(Grik4-cre)G32-4Stl
• Name: transgene insertion G32-4, Susumu Tonegawa
• MGI ID: MGI:2387441
• Synonyms: G32-4 Cre, Grik4-Cre, KA1-Cre, KA-cre, Tg(Grik4-Cre)G32-4Stu
• Transgene: Tg(Grik4-cre)G32-4Stl Location: unknown
• Alliance: Tg(Grik4-cre)G32-4Stl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Grik4-cre)G32-4Stl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Grik4

• Mutation details: The transgenic constuct consisted of the Grik4 promoter and exons 1 and 2 adjoined to the cre recombinase coding region. The Grik4 promoter was shown to drive expression in the CA3 pyramidal cell layer by staining of a mouse also harboring a lacZ reporter transgene that is expressed upon cre mediated recombination. (J:77718)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grik4 (species not specified) Summary of all recombinase alleles driven by Grik4. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:77718 Nakazawa K, et al., Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science. 2002 Jul 12;297(5579):211-8
• All: 68 reference(s)