Tg(Pdx1-cre)1Herr
Transgene Detail

Summary

• Symbol: Tg(Pdx1-cre)1Herr
• Name: transgene insertion 1, Pedro Luis Herrera
• MGI ID: MGI:2387562
• Synonyms: Pdx1^Late-Cre, PDX1Pr-Cre
• Transgene: Tg(Pdx1-cre)1Herr Location: unknown
• Alliance: Tg(Pdx1-cre)1Herr page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdx1-cre)1Herr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pdx1

• Mutation details: The 4.5 kb region containing Pdx1 regulatory sequences was used to drive expression of a cre recombinase constructed modified with a nuclear localization signal upstream of a human hGH minigene. The Pdx1 promoter drives expression in the pancreas. Mosaic cre expression is first observed in the pancreatic epithelium at E11.5. Expression continues to be mosaic at E12.5. (J:78865, J:108521)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78865 Herrera PL, Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development. 2000 Jun;127(11):2317-22
• All: 41 reference(s)