Tg(Ins2-cre)23Herr
Transgene Detail

Summary

• Symbol: Tg(Ins2-cre)23Herr
• Name: transgene insertion 23, Pedro Luis Herrera
• MGI ID: MGI:2387567
• Synonyms: Ins(cre), InsCre, InsPr-Cre, (INSPr)-Cre, RipCre, RIP-cre, RIP-Cre^Herr
• Transgene: Tg(Ins2-cre)23Herr Location: unknown
• Alliance: Tg(Ins2-cre)23Herr page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ins2-cre)23Herr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: A 0.6 kb fragment containing the rat insulin promoter was adjoined to the cre recombinase coding sequence to drive expression in pancreatic cells. (J:78865)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins2 (rat) Summary of all recombinase alleles driven by Ins2. Comparative matrix view of recombinase activities Alliance rat Ins2 gene page

Disease models

Expression

In Mice Carrying this Mutation:

21 assay results 12 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Ins2-cre)23Herr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:69321 Herrera PL, et al., Two transgenic approaches to define the cell lineages in endocrine pancreas development. Mol Cell Endocrinol. 1998 May 25;140(1-2):45-50
• All: 167 reference(s)